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  • Title: Mixture estimation and the neurophysiological quantal hypothesis.
    Author: Smith BR.
    Journal: Biometrics; 1993 Jun; 49(2):643-51. PubMed ID: 8369397.
    Abstract:
    Quantal release models provide a mechanistic description of the process by which neurotransmitter is released from the nerve cell. The usual such model assumes that the quantity of transmitter released after nerve depolarization follows a finite mixture distribution with an unknown number of components, and with constraints on component means and variances. General procedures for estimating the dimension of a finite mixture model are discussed, and applied to the analysis of a quantal release data set.
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