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  • Title: Thrombolysis in peripheral arterial graft occlusion.
    Author: Bandyk DF.
    Journal: Can J Surg; 1993 Aug; 36(4):372-8. PubMed ID: 8370020.
    Abstract:
    Acute thrombosis of arterial bypass grafts in the lower extremities poses a significant risk for limb loss. Graft salvage in patients affected by this complication remains a challenge. The vascular surgeon must consider the spectrum of treatment options (thrombolysis, thrombectomy, graft replacement) in managing acute graft thrombosis. Oral anticoagulants should be considered in patients with low-flow polytetrafluoroethylene (PTFE) grafts and after successful thrombolysis, with or without revision. The role of thrombolytic therapy for occluded vein grafts is less clear, but successful lysis is likely in patients who present within 48 hours of graft thrombosis and the etiology includes a correctable graft stenosis.
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