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  • Title: Isolation of camelliaside C from "tea seed cake" and inhibitory effects of its derivatives on arachidonate 5-lipoxygenase.
    Author: Sekine T, Arai Y, Ikegami F, Fujii Y, Shindo S, Yanagisawa T, Ishida Y, Okonogi S, Murakoshi I.
    Journal: Chem Pharm Bull (Tokyo); 1993 Jun; 41(6):1185-7. PubMed ID: 8370116.
    Abstract:
    A new flavonol glycoside, camelliaside C, was isolated from "tea seed cake" prepared from the defatted seeds of Camellia sinensis O. Kuntze. The structure was determined as kaempferol 3-O-beta-D-galactopyranosyl-(1-->2)-beta-D-glucopyranoside by spectroscopic methods (FAB-MS, UV, IR, 1H- and 13C-NMR) and the enzymatic transformation of camelliaside C to astragalin. Camelliaside C showed an inhibitory effect on the arachidonate 5-lipoxygenase of RBL-1 cells (IC50:1.4 x 10(-4)M) as did camelliaside A and B isolated from the same product.
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