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  • Title: Dosimetry of iodine-123 iomazenil in humans.
    Author: Verhoeff NP, Busemann Sokole E, Hengst D, Stubbs JB, van Royen EA.
    Journal: Eur J Nucl Med; 1993 Jul; 20(7):580-4. PubMed ID: 8370378.
    Abstract:
    The distribution of the central benzodiazepine receptor specific ligand iodine-123 iomazenil was investigated in seven human adults from whole-body scans, blood samples and urine collected up to 24 h after injection. Using 12 source organs, the MIRD method was applied to calculate the absorbed radiation dose of the radioligand in various organs. The urinary bladder wall (0.15 mGy/MBq), lower large intestinal wall (0.071 mGy/MBq) testes (0.044 mGy/MBq) and upper large intestined wall (0.038 mGy/MBq) received the highest absorbed doses. The average effective dose equivalent of 123I-IBZM for adults was estimated to be 0.033 mSv/MBq.
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