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Title: Hypocomplementemic urticarial vasculitis syndrome, Jaccoud's syndrome, valvulopathy: a new syndromic combination. Author: Palazzo E, Bourgeois P, Meyer O, De Bandt M, Kazatchkine M, Kahn MF. Journal: J Rheumatol; 1993 Jul; 20(7):1236-40. PubMed ID: 8371228. Abstract: We describe 3 cases of hypocomplementemic urticarial vasculitis syndrome (HUVS) with Jaccoud's hands deformity and cardiac valve disease (aortic regurgitation, mitral regurgitation, mitral disease). In one case, the valve lesions required valve replacement and later a heart transplant. Valve disease and articular deformities developed 2 and 4 years, respectively, after the onset of HUVS. This as yet undescribed combination of diseases suggests a new syndrome. Pathogenesis of periarticular and cardiac lesions is unknown. The role of Clq and anti-Clq antibody is discussed.[Abstract] [Full Text] [Related] [New Search]