These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Arterial infusion chemotherapy of 5-FU and leucovorin for patients with liver metastases from colorectal cancer].
    Author: Yamamura T, Hanai A, Oikawa H, Matsuzaki H, Kikuchi K, Akaishi O, Seo K, Ozasa T, Katayama K.
    Journal: Gan To Kagaku Ryoho; 1993 Aug; 20(11):1516-9. PubMed ID: 8373209.
    Abstract:
    Fifteen patients with liver metastases from colorectal cancer were treated by arterial infusion of 5-FU and leucovorin. Two regimens were performed. One was weekly bolus infusion of leucovorin following bolus infusion of 5-FU (bolus group), the other was 5 days continuous infusion of 5-FU and leucovorin in 3 weeks (continuous group). One PR was obtained both in the bolus group and in the continuous groups. The objective response rate was 11% in the bolus group and 20% in the continuous group. The one- and 2-year survival rates for these patients were 40% and 0% in the bolus group, and 80% and 60% in the continuous group, respectively. These results suggest that continuous arterial infusion of 5-FU and leucovorin was more effective than individual bolus arterial infusion of leucovorin and 5-FU for patients with liver metastases from colorectal cancer.
    [Abstract] [Full Text] [Related] [New Search]