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  • Title: Molecular cloning of crustacean red pigment concentrating hormone precursor.
    Author: Linck B, Klein JM, Mangerich S, Keller R, Weidemann WM.
    Journal: Biochem Biophys Res Commun; 1993 Sep 15; 195(2):807-13. PubMed ID: 8373416.
    Abstract:
    A cDNA encoding the precursor of the red pigment concentrating hormone (RPCH) of the shore crab, Carcinus maenas, was isolated and sequenced. The predicted preprohormone sequence consists of a putative 25 amino acid signal peptide, the eight amino acid RPCH sequence followed by a Gly as amide donor, a dibasic processing site and a 74 residue peptide of unknown function, referred to as RPCH-precursor-related peptide (RPRP). In in situ hybridisation experiments, the RPCH gene transcript could be localised in two clusters of neurons in the medulla terminalis of the eyestalk.
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