These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Effect of exogenous thyroxine on timing of seasonal reproductive transitions in ewes.
    Author: O'Callaghan D, Wendling A, Karsch FJ, Roche JF.
    Journal: Biol Reprod; 1993 Aug; 49(2):311-5. PubMed ID: 8373954.
    Abstract:
    The thyroid gland is necessary for the transition from the breeding season to anestrus in the ewe, but the importance of seasonal changes in thyroxine in this process is not known. The objective of this experiment was to determine the effects of exogenous thyroxine during the breeding season on the time of the transition to anestrus and on the onset of the subsequent breeding season in ewes maintained on natural photoperiod. Cyclic Galway ewes were blocked on the basis of body weight and randomly allocated to the following groups: 1) untreated controls (n = 11), 2) placebo-injected controls (n = 9), and 3) ewes injected daily with thyroxine from the middle of the breeding season until the onset of anestrus (n = 10). Reproductive state was assessed from serum progesterone concentrations determined twice weekly until the breeding season had ended in placebo-injected controls, and until the onset of the subsequent breeding season in untreated and thyroxine-injected ewes. The mean (+/- SEM) date of onset of anestrus did not differ between untreated ewes (April 19 +/- 9 days) and placebo-injected controls (April 15 +/- 9 days; p > 0.05), but occurred earlier in ewes injected with thyroxine (February 28 +/- 6 days; p < 0.001). Thyroxine treatment during the breeding season, however, did not affect the onset of the subsequent breeding season. These data indicate that supplementary thyroxine during the breeding season can advance anestrus and thus shorten the duration of the breeding season.(ABSTRACT TRUNCATED AT 250 WORDS)
    [Abstract] [Full Text] [Related] [New Search]