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  • Title: A GM-CSF/IL-3 fusion protein promotes neutrophil and platelet recovery in sublethally irradiated rhesus monkeys.
    Author: Williams DE, Dunn JT, Park LS, Frieden EA, Seiler FR, Farese AM, Macvittie TJ.
    Journal: Biotechnol Ther; 1993; 4(1-2):17-29. PubMed ID: 8374510.
    Abstract:
    The effects of a human GM-CSF/IL-3 fusion protein (PIXY321) were examined in a primate model of rebound hematopoiesis following sublethal irradiation. The results demonstrated an enhanced rate of both neutrophil and platelet regeneration, as well as functional activation of circulating neutrophils.
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