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  • Title: [Modification of ischemia and reperfusion damage of skeletal muscles with allopurinol: in vivo 31P MR spectroscopy of the posterior limb of the rat].
    Author: Gürke L, Marx A, Erhard P, Sutter PM, Landmann J, Heberer M.
    Journal: Helv Chir Acta; 1993 Jun; 59(5-6):877-80. PubMed ID: 8376157.
    Abstract:
    The effect of Allopurinol on energy metabolism (re-utilisation of hypoxanthine) was studied in a in vivo skeletal muscle ischemia rat model by 31-P-MR spectroscopy. Allopurinol-treatment showed no benefit to the kinetics of PCr/(Pi + PCr) and ATP/(Pi + PCr). The role of re-utilisation of hypoxanthine has to be further investigated.
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