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  • Title: [Pioneer experience with buflomedil in the form of retrograde venous pulse therapy for treatment of ischemia and severe extremity infections].
    Author: Cavini-Ferreira PC.
    Journal: Wien Med Wochenschr; 1993; 143(7-8):193-4. PubMed ID: 8379175.
    Abstract:
    Retrograde venous pulse therapy (RVP) allows faster healing of the infection, shortening of hospitalization time, and recovering of the chronic ischemia. RVP als has a dramatic effect on diabetic foot by passing the functional disorder of the microcirculation produced by diabetic neuropathy and micro-angiopathy, with important reduction of amputation rates in these patients. We credit these results to the very high concentration of Buflomedil provided by RVP in the target tissues, which allows the penetration and impregnation of other active substances (7).
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