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  • Title: Duodenal denervation in dogs. Effect upon gastroduodenal emptying and motility, Heidenhain pouch acid secretion and serum gastrin concentration.
    Author: Boné J, Ornsholt J, Brandsborg O, Brandsborg M, Mikkelsen K.
    Journal: Digestion; 1977 Feb; 15(2):129-35. PubMed ID: 838184.
    Abstract:
    In dogs with the continuity of the stomach and duodenum intact the peristaltic and antiperistaltic waves in the duodenum disappeared completely and gastric emptying became faster after selective duodenal denervation. No significant changes occurred in fasting and food-stimulated Heidenhain pouch acid secretion or in serum concentration. It is concluded that the duodenal vagal nerves have importance for duodenal motility, but do not influence the gastrin release from the antrum and the small bowel or the acid secretion from a Heidenhain pouch.
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