These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Actions of dalargin upon single unit activity in the ampullae of Lorenzini of the skate Raja clavata.
    Author: Andrianov GN, Akoev GN, Braun HA, Ryzhova IV, Voigt KH, Sherman NO.
    Journal: Neuroreport; 1993 Jan; 4(1):53-4. PubMed ID: 8384018.
    Abstract:
    In the present study we have shown by single afferent unit recording in electroreceptors of skates (the ampullae of Lorenzini) that the synthetic analogue of leu-enkephalin, dalargin (DAL) at concentrations between 10(-6)-10(-10) M cause a concentration-dependent decrease in the resting discharge frequency as well as a decrease in stimulus evoked responses. The specific opiate antagonist naloxone (NAL, 10(-6) M) antagonizes responses induced by DAL. DAL depresses the excitatory action of L-glutamate (L-GLU). The data obtained speak in favour of the presence of opiate receptors at the synaptic membrane of the ampullae of Lorenzini.
    [Abstract] [Full Text] [Related] [New Search]