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  • Title: The avian rotavirus Ty-1 Vp7 nucleotide and deduced amino acid sequences differ significantly from those of Ch-2 rotavirus.
    Author: Kool DA, Holmes IH.
    Journal: Arch Virol; 1993; 129(1-4):227-34. PubMed ID: 8385915.
    Abstract:
    The Vp7 gene of the avian strain Ty-1, which is classified as G7 serotype, was sequenced and the amino acid sequence deduced. The gene is 1065 nucleotides long with a long open reading frame of 987 nucleotides producing a protein 329 amino acids in length. The amino acid homology of the Ty-1 Vp7 protein to that of the avian Ch-2 Vp7 was 70%. The A, B, and C variable epitope regions of Ty-1 were unique compared to those of Ch-2 and other strains representing the 14G serotypes. The low 53% homology of the A and C regions of Ty-1 and Ch-2 would suggest that Ty-1 may be of a different serotype to the G7 reference strain Ch-2.
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