These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Is pure red cell aplasia (PRCA) a clonal disorder?
    Author: Sivakumaran M, Bhavnani M, Stewart A, Roberts BE, Geary GC.
    Journal: Clin Lab Haematol; 1993; 15(1):1-5. PubMed ID: 8386075.
    Abstract:
    Pure red cell aplasia (PRCA) is an uncommon disorder, many cases lacking a well defined aetiology. This report describes three cases of PRCA (two idiopathic and one associated with B-CLL) who were investigated to assess the possibility of their PRCA being associated with a clonal proliferation of T-lymphocytes. The results show that one patient had evidence of T-cell receptor (TCR) gamma chain rearrangement, and the other had a TCR delta chain rearrangement. These two cases raise the possibility of PRCA being associated with a clonal proliferation of T-cells and further studies are warranted.
    [Abstract] [Full Text] [Related] [New Search]