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  • Title: Silent renal damage in symptom-free siblings of children with vesicoureteral reflux: assessment with technetium Tc 99m dimercaptosuccinic acid scintigraphy.
    Author: Buonomo C, Treves ST, Jones B, Summerville D, Bauer S, Retik A.
    Journal: J Pediatr; 1993 May; 122(5 Pt 1):721-3. PubMed ID: 8388446.
    Abstract:
    Sixteen symptom-free siblings of children with vesicoureteral reflux were found to have the condition and underwent renal scintigraphy with technetium 99m dimercaptosuccinic acid. Of these 16 children, 6 had scintigraphic evidence of renal damage. Screening for vesicoureteral reflux in siblings of children known to have the condition should therefore be carried out early in life; when reflux is present, an immediate assessment of the renal parenchyma should be made.
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