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  • Title: Calmodulin-dependent phosphorylation and dephosphorylation during fertilization in Dictyostelium discoideum.
    Author: Lydan MA, O'Day DH.
    Journal: Biochem Biophys Res Commun; 1993 May 14; 192(3):1073-8. PubMed ID: 8389540.
    Abstract:
    Many calmodulin-dependent biological phenomena are regulated by calmodulin-dependent phosphorylation and dephosphorylation. In Dictyostelium discoideum, cell and pronuclear fusion during fertilization are both calmodulin-dependent biomembrane fusion events. Calmodulin-dependent phosphorylation and dephosphorylation activity was present in sexually developing D. discoideum cells suggesting it has a role during fertilization. In support of this, a discrete calmodulin-independent kinase was present only during cell and pronuclear fusion.
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