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  • Title: [Effect of calmodulin on the activity of NAD-kinase from rabbit liver].
    Author: Bulygina ER, Voronina OL, Telepneva VI.
    Journal: Biokhimiia; 1993 Apr; 58(4):632-5. PubMed ID: 8389607.
    Abstract:
    It has been shown that rabbit liver NAD-kinase is a Ca(2+)-dependent, calmodulin-regulated enzyme. Differences were found between the sensitivity of the alpha- and beta-forms of the enzyme to calmodulin. The maximal activation of the NAD-kinase alpha-form was observed at a calmodulin/NAD-kinase ratio equal to 2, that of the beta-form--at 4. Further increases in the above parameter (up to 10) had no effect on the activity of the alpha-form, whereas that of the beta-form dropped down to the initial (basal) level.
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