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  • Title: Persistence of human papillomavirus type 6e in adult multiple laryngeal papilloma and the counterpart false cord of an interferon-treated patient.
    Author: Ogura H, Watanabe S, Fukushima K, Baba Y, Masuda Y, Fujiwara T, Yabe Y.
    Journal: Jpn J Clin Oncol; 1993 Apr; 23(2):130-3. PubMed ID: 8390585.
    Abstract:
    Human papillomavirus (HPV) type 6e DNA was detected in a laryngeal papilloma, in a papilloma recurring after an interval of six years and in the counterpart clinically-normal false cord of the same patient. No detectable subgroup change of HPV DNA occurred during the clinical course, which included therapy by CO2 laser followed by intramuscular alpha-interferon injection. The data demonstrated a single subtype of HPV to have persisted, and the prevention of a recurrence of laryngeal papilloma during our patient's long clinical course to have failed, in spite of the interferon treatment.
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