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Title: Detection of HCV-RNA in saliva of patients with chronic hepatitis C. Author: Couzigou P, Richard L, Dumas F, Schouler L, Fleury H. Journal: Gut; 1993; 34(2 Suppl):S59-60. PubMed ID: 8390957. Abstract: Previous studies have provided conflicting results on the presence of hepatitis C virus-RNA in saliva. In this study, 23 (62%) of 37 patients tested positive for hepatitis C virus-RNA in saliva, using polymerase chain reaction analysis. A slightly greater proportion had a sporadic rather than a parenteral origin of chronic hepatitis C. These results provide a biological basis for saliva as a possible source of hepatitis C virus (HCV) infection, but do not necessarily imply transmission by this route.[Abstract] [Full Text] [Related] [New Search]