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  • Title: [Serological property of perchloric acid-soluble glycoprotein fractions of human meconium].
    Author: Uchide N, Ohyama K, Yamakawa T, Watanabe H, Hirakawa S, Yoneyama K, Ohkuma S.
    Journal: Yakugaku Zasshi; 1993 Jul; 113(7):532-6. PubMed ID: 8396178.
    Abstract:
    Perchloric acid-soluble fractions (PASFs) were separated, in yields of 87.0-151.9 mg per 1.0 g of wet meconium sample, from six samples of human meconium, and identified as glycoproteins having 41.2-74.1% carbohydrate by chemical composition analysis. Six PASFs reacted with anti-A, -B, -Lea and -Leb sera, but did not react with anti-M and -N sera. These PASFs alos reacted with many lectins such as DBA, UEA-I, Vicia graminea lectin (VGA), Vicia unijuga lectin (VUA), Con A, WGA, RCA-I, PHA-E, SBA, SJA, and influenza A and B viruses. The serological results show that six PASFs contained VGA or VUA-binding (Vgu) glycoproteins as new oncofetal substances, but did not contain M and N blood group substances.
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