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  • Title: Chronic human schistosomiasis mansoni. Pathology of the Disse's space.
    Author: Grimaud JA, Borojevic R.
    Journal: Lab Invest; 1977 Mar; 36(3):268-73. PubMed ID: 839738.
    Abstract:
    In chronic human schistosomiasis mansoni, the entire hepatic lobule is involved. The hepatovascular barrier is modified and shows hepatic sinusoids with hypertrophy and stratification of endothelium, basement membrane-like deposits, perisinusoidal fibrosis, diminution of hepatocellular microvilli and hepatocellular clasmatosis into the sinusoidal circulation. This transformation of an open circulation to a partly closed one may decrease the blood hepatocyte exchanges in schistosomiasis mansoni.
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