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  • Title: [The effect of hyperparathyroidism on the function of the hypothalamo-hypophyseal-adrenocortical system in unilaterally adrenalectomized rats].
    Author: Drzhevetskaia IA, Surkhobi ZG, Dzhandarova TI.
    Journal: Fiziol Zh Im I M Sechenova; 1993 Jul; 79(7):109-14. PubMed ID: 8401662.
    Abstract:
    Hyperparathyroidism was shown to activate the hypothalamo-hypophyseal-adrenocortical system (HHACS) in rats, intensifying the compensatory adrenal hypertrophy in unilaterally adrenalectomised rats, rising the level of 11-oxycorticosteroids in their plasma and adrenal gland, activating the production of corticoliberin in hypothalamus and corticotrophin in hypophysis. The HHACS activity was the highest in 3-month-old rats.
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