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  • Title: Tc-99m sestamibi and other agents in the detection of metastatic medullary carcinoma of the thyroid.
    Author: Lebouthillier G, Morais J, Picard M, Picard D, Chartrand R, D'Amour P.
    Journal: Clin Nucl Med; 1993 Aug; 18(8):657-61. PubMed ID: 8403695.
    Abstract:
    The 10-year survival rate for medullary carcinoma of the thyroid (MCT) is 50%; thus, good tumor-seeking radiopharmaceuticals are needed to localize foci of recurrence and metastasis during follow-up. Two patients with metastatic MCT were studied with Tl-201, I-131 MIBG, Tc-99m (V)-DMSA, and Tc-99m MIBI. A SPECT study with the latter agent allowed the visualization and precise localization of a metastatic mediastinal lymph node. More studies need to be done to evaluate the role of Tc-99m MIBI in the detection of recurrence and metastases of MCT.
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