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  • Title: An interactive graphics system for real-time investigation and multivariate data portrayal for complex pedigree data systems.
    Author: Newton CM.
    Journal: Comput Biomed Res; 1993 Aug; 26(4):327-43. PubMed ID: 8403857.
    Abstract:
    GRIFFIN (graphics investigation of familial information), an interactive graphics system for exploratory investigation of data on individuals associated by familial relationships, was designed to provide genetic epidemiologists a flexible, rapidly responsive tool for viewing and guiding exploration of complex databases in the context of familiar pedigree structures. It graphically portrays both categorical and multivariate scalar data on individuals in those structures. The display can be inverted to show all ancestors and descendants of any individual the user designates. It provides cues to censored information when bushy pedigrees cannot be fully displayed without sacrificing legibility. These guide users on where to next invert the system. Investigators may translate/zoom the display, vary the mode of representing data, point to individuals to obtain displays of alphameric information about them, etc. Developed in Fortran using IBM's GDDM graphics subroutines for an IBM 3090 mainframe, GRIFFIN's design anticipates porting to smaller systems.
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