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  • Title: Evaluation of a monoclonal antibody-based enzyme immunoassay for early detection of herpes simplex virus genital infection.
    Author: Bornstein J, Ben-Porath E, Nizri M, Satinger Y, Sperber S, Abramovici H.
    Journal: Isr J Med Sci; 1993 Aug; 29(8):445-8. PubMed ID: 8407269.
    Abstract:
    A monoclonal antibody-based enzyme immunoassay test for detection of herpes simplex virus (HSV) type-common antigen was evaluated in 40 women with vulvar lesion suspicious for genital HSV infection. The assay gave interpretable readings in 90% of the cases, with sensitivity and specificity of 100% and 92% respectively, a negative predictive value of 100%, and a positive predictive value of 75%. With a few limitations, the assay may be used for early diagnosis of genital HSV infection.
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