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Title: Pharmacokinetics of antidepressants: why and how they are relevant to treatment. Author: Preskorn SH. Journal: J Clin Psychiatry; 1993 Sep; 54 Suppl():14-34; discussion 55-6. PubMed ID: 8407856. Abstract: The pharmacokinetics of antidepressants are reviewed with special emphasis on clinical applicability. There are substantial pharmacokinetic differences among the five major classes. Pharmacokinetic differences between members of a specific class are usually modest except for serotonin selective reuptake inhibitors. Between members of this class pharmacokinetic differences are the major distinguishing variables and have clinically important consequences.[Abstract] [Full Text] [Related] [New Search]