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  • Title: Pattern of interleukins in minimal-change nephrotic syndrome of childhood.
    Author: Saxena S, Mittal A, Andal A.
    Journal: Nephron; 1993; 65(1):56-61. PubMed ID: 8413792.
    Abstract:
    Assays of interleukin-1 (IL-1) and IL-2 were done in supernatants from phytohaemagglutinin-activated lymphocyte cultures from 10 children suffering from minimal-change nephrotic syndrome (MCNS) to assess their role in the aetiopathogenesis of this disorder. Increased levels of IL-1 and IL-2 had been found in supernatants from patients having MCNS compared with controls, suggesting a significant role of these cytokines in the immunopathogenesis of proteinuria in this syndrome.
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