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  • Title: A peptide corresponding to the N-terminal 13 residues of T4 lysozyme forms an alpha-helix.
    Author: McLeish MJ, Nielsen KJ, Wade JD, Craik DJ.
    Journal: FEBS Lett; 1993 Jan 11; 315(3):323-8. PubMed ID: 8422925.
    Abstract:
    Solid-phase methods have been used to synthesize LYS(1-13), a peptide corresponding to the first 13 residues of T4 lysozyme. 2D 1H NMR techniques were used to investigate its solution structure in the presence of SDS micelles. The identification of numerous medium-range NOESY crosspeaks and several slowly exchanging NH protons indicated the presence of an alpha-helical structure. This was confirmed by simulated annealing calculations performed using XPLOR.
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