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  • Title: Osteocalcin levels in maternal and cord blood.
    Author: Seki K, Makimura N, Mitsui C, Nagata I.
    Journal: Obstet Gynecol; 1993 Feb; 81(2):189-90. PubMed ID: 8423947.
    Abstract:
    OBJECTIVE: To measure osteocalcin levels in fetal and maternal blood. METHODS: Osteocalcin was measured by radioimmunoassay in paired maternal and umbilical venous and arterial blood obtained at term deliveries. RESULTS: Umbilical venous osteocalcin levels (mean +/- standard deviation) were significantly higher than arterial levels (10.28 +/- 4.99 versus 3.85 +/- 2.27 micrograms/L). Umbilical venous but not arterial levels of osteocalcin were significantly higher than maternal values (2.54 +/- 1.19 micrograms/L). CONCLUSION: Higher osteocalcin levels in umbilical venous blood than in umbilical arterial blood suggest that the placenta may be the main source of osteocalcin in late fetal life.
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