These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Characterization of the promoter of human prostaglandin H synthase-1 gene.
    Author: Wang LH, Hajibeigi A, Xu XM, Loose-Mitchell D, Wu KK.
    Journal: Biochem Biophys Res Commun; 1993 Jan 29; 190(2):406-11. PubMed ID: 8427584.
    Abstract:
    The gene of human prostaglandin H synthase-1 (PGHS-1,EC 1.14.99.1) was isolated from a human cosmid library and was contained in two overlapping clones. Multiple transcriptional start sites were identified. The major one located 136 bases upstream from the ATG initiation codon. The promoter region contains no canonical TATA box but possesses a high G+C content. These observations suggest that PGHS-1 gene has the characteristics of a housekeeping gene. Both 0.8 and 0.4 kb of the 5'-flanking sequence of the PGHS-1 gene can confer transcriptional activity.
    [Abstract] [Full Text] [Related] [New Search]