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  • Title: Percutaneous ultrasound-guided biopsy. Fine needle biopsy, cutting needle biopsy, or both?
    Author: Tikkakoski T, Päivänsalo M, Siniluoto T, Hiltunen S, Typpö T, Jartti P, Apaja-Sarkkinen M.
    Journal: Acta Radiol; 1993 Jan; 34(1):30-4. PubMed ID: 8427745.
    Abstract:
    The results of 155 US-guided cutting needle biopsies, mainly of abdominal and transthoracic lesions, were reviewed to assess the diagnostic accuracy of the method. A fine needle biopsy (FNB) was additionally performed in 99 of the patients. Sufficient material for histologic and cytologic analysis was obtained in 88% (137/155) and 98% (97/99), and a correct benign or malignant diagnosis was made in 87% and 88%, respectively. Among the 99 combined biopsies the corresponding figures were 100% and 97%, respectively. The proportions of inconclusive and false-negative results among histologic samples were 0% and 4% (2/57), in FNBs 7% (7/99) and 5% (3/56), and in combined examinations 3% (3/99) and 0%. One major complication, Streptococcus faecalis sepsis, occurred. The combined use of FNB and histologic biopsy increases the proportion of correct diagnoses about 10% without increasing the complications.
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