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  • Title: Neonatal rat liver contains low concentrations of Cu-Zn superoxide dismutase protein and mRNA.
    Author: Yang FL, David EA, DiSilvestro RA.
    Journal: Biochim Biophys Acta; 1993 Feb 13; 1156(2):232-4. PubMed ID: 8427881.
    Abstract:
    Copper (Cu) distribution among organs and among individual proteins can differ sharply between neonates and adults. The present study found low mRNA and protein levels for neonate rat liver cytosolic Cu-zinc (Zn) superoxide dismutase (SOD), normally among the largest single copper pools in adult rats. Thus, regulation of Cu-Zn SOD mRNA levels contribute to life stage differences in copper distribution.
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