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Title: Localization of the human poly(A)-binding protein gene (PAB1) to chromosomal regions 3q22-q25, 12q13-q14, and 13q12-q13 by in situ hybridization. Author: Morris CM, Bodger MP. Journal: Genomics; 1993 Jan; 15(1):209-11. PubMed ID: 8432538. Abstract: A cDNA clone encoding the human polyadenylate-binding protein (PABP) was isolated and mapped to the genome by in situ hybridization. The cDNA was found to bind preferentially to chromosomal regions 3q22-q25, 12q13-q14, and 13q12-q13. In addition, Southern blot analysis of genomic DNA using a PABP cDNA probe revealed a complex pattern of bands. The results indicate that PABP belongs to a multigene family of related sequences.[Abstract] [Full Text] [Related] [New Search]