These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: In vitro selection of optimal DNA substrates for T4 RNA ligase.
    Author: Harada K, Orgel LE.
    Journal: Proc Natl Acad Sci U S A; 1993 Feb 15; 90(4):1576-9. PubMed ID: 8434020.
    Abstract:
    We have used in vitro selection techniques to characterize DNA sequences that are ligated efficiently by T4 RNA ligase. We find that the ensemble of selected sequences ligated about 10 times as efficiently as the random mixture of sequences used as the input for selection. Surprisingly, the majority of the selected sequences approximated a well-defined consensus sequence.
    [Abstract] [Full Text] [Related] [New Search]