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  • Title: Allelochemicals in plant foods and feedingstuffs: 1. Nutritional, biochemical and physiopathological aspects in animal production.
    Author: Aletor VA.
    Journal: Vet Hum Toxicol; 1993 Feb; 35(1):57-67. PubMed ID: 8434459.
    Abstract:
    Several allelochemicals (anti-nutritional/anti-quality factors) contained in some plant foods and feedingstuffs are outlined. These include the trypsin and amylase inhibitors, hemagglutinins, gossypol, cyanogenic glycosides, tannins, oxalates, phytin, saponins, glucosinolates, estrogens, coumarins, alkaloids and aflatoxins. The nutritional, biochemical and physiopathological implications of their ingestion in a wide range of animals are reviewed. These include impaired growth, feed consumption, efficiency of feed utilization, alterations of normal enzyme activities, organ atrophy, necrotic changes, lesions and changes in normal hematological indices. The induction of increased dietary requirements for such nutrients as methionine, lysine, vitamins and divalent ions (eg Fe, Ca, Mg and Zn) by some of these factors is discussed. Ameliorative measures aimed at minimizing the concentrations and anti-nutritional effects of these factors are processing and including additives in the diet, or genetic manipulations. There is a need to prevent both functional and nutritional damage of food proteins and other nutrients arising from excessive heat treatment.
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