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  • Title: Reduction of fatty acid hydroperoxides by human parotid saliva.
    Author: Terao J, Nagao A, Yuki H, Itoh Y.
    Journal: Lipids; 1993 Feb; 28(2):121-4. PubMed ID: 8441337.
    Abstract:
    Arachidonic acid hydroperoxide (15-hydroperoxyeicosatetraenoic acid; 15-HPETE) was introduced into human parotid saliva and incubated at 37 degrees C. Straight phase high-performance liquid chromatography analysis of the reaction mixture showed that 15-HPETE was detoxified to its reduced form, 15-hydroxyeicosatetraenoic acid, in the presence of glutathione. Therefore, it is concluded that human parotid saliva possesses fatty acid hydroperoxide-reducing ability. However, its effectiveness was found to be lower than that of blood plasma.
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