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  • Title: Inhibition of the scarlet fever exanthem in concurrent varicella and group A streptococcus infection.
    Author: Friedman MA, Klein JD, Eppes SC.
    Journal: Clin Infect Dis; 1993 Feb; 16(2):286-7. PubMed ID: 8443308.
    Abstract:
    An atypical scarlet fever exanthem was noted in a 5-year-old child with varicella complicated by secondary group A beta-hemolytic streptococcus pneumonia and empyema. The rash consisted of symmetrical, concentric, circular exanthem-free zones surrounding individual varicella vesicles. The possible role of virus-induced interferon in locally modifying the effect of streptococcal pyrogenic exotoxin is explored.
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