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  • Title: Acute right ventricular heart failure in a patient with renal cell carcinoma after interferon therapy.
    Author: Kramers C, de Mulder PH, Barth JD, Wagener DJ.
    Journal: Neth J Med; 1993 Feb; 42(1-2):65-8. PubMed ID: 8446228.
    Abstract:
    In a patient with diffuse pulmonary metastases of a renal cell carcinoma the development of severe pulmonary hypertension is described after reaching a complete remission during treatment with r-IFN-alpha 2c and rIFN-gamma. Rechallenge with interferon after the discovery of recurrent disease did not lead to deterioration of the cardiopulmonary condition. Possible causative mechanisms are discussed.
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