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  • Title: Relief of sickle cell priapism by hydralazine. Report of a case.
    Author: Baruchel S, Rees J, Bernstein ML, Goodyer P.
    Journal: Am J Pediatr Hematol Oncol; 1993 Feb; 15(1):115-6. PubMed ID: 8447552.
    Abstract:
    We report a 16-year-old Tanner IV male with homozygous hemoglobin S who presented with recurrent episodes of priapism unresponsive to standard therapy with hydration, analgesia, and exchange transfusion. He had a complete resolution of his symptoms with hydralazine therapy. We therefore suggest a trial of vasodilator therapy for recurrent sickle cell priapism before attempting surgical therapy.
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