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Title: Brominated indole alkaloids from the marine tunicate Pseudodistoma arborescens. Author: Chbani M, Païs M, Delauneux JM, Debitus C. Journal: J Nat Prod; 1993 Jan; 56(1):99-104. PubMed ID: 8450325. Abstract: Chemical investigation of the cytotoxic CH2Cl2-soluble extract of the marine tunicate Pseudodistoma arborescens led to the isolation of four brominated indole alkaloids, arborescidines A [1], B [2], C [3], and D [4], which were characterized by their spectral data, especially 2D nmr. Only arborescidine D [4] showed moderate activity (IC50 3 micrograms/ml) in vitro against the growth of KB human buccal carbinoma cells.[Abstract] [Full Text] [Related] [New Search]