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  • Title: Effect of prostaglandin F2alpha-THAM in the bitch.
    Author: Sokolowski JH, Geng S.
    Journal: J Am Vet Med Assoc; 1977 Mar 01; 170(5):536-7. PubMed ID: 845082.
    Abstract:
    The subcutaneous median lethal dosage for prostaglandin F2alpha for the Beagle bitch was determined to be 5.13 mg/kg, using a sequential experimental design. Clinical signs and gross and histologic findings were consistent with a diagnosis of shock syndrome. It was concluded that prostaglandin F2alpha could be used to develop a pharmacologically controlled shock model.
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