These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Influence of diet on lactate, alanine and serine turnover and incorporation into glucose in the dog.
    Author: Belo PS, Romsos DR, Leveille GA.
    Journal: J Nutr; 1977 Mar; 107(3):397-403. PubMed ID: 845677.
    Abstract:
    Four diets containing 0 to 62% of energy from carbohydrate and 24% to 48% of energy from protein were fed to young dogs. The influence of these diets on the turnover of [U-14C]-L-lactate, [U-14C]-L-alanine and [U-14C]-L-serine and on the incorporation of these gluconeogenic precursors into plasma glucose of the dog was established. Blood lactate levels were lowered when high-protein diets were fed but were not influenced by the level of carbohydrate in the diet or by a 48-hour fast. Plasma alanine and serine levels were elevated in dogs fed the high-protein diets and were lowered by a 48-hour fast. Turnover of lactate was increased in dogs fed high-carbohydrate diets whereas turnover of alanine and serine was increased in dogs fed the high-protein diets. Following a 48-hour fast, 14C-lactate conversion to plasma glucose was lower in dogs fed the high-protein diets than in dogs fed the lower protein diets whereas 14C-alanine and 14C-serine conversion to plasma glucose was increased in dogs fed the high-protein. Thus, the diet consumed altered the relative importance of these gluconeogenic precursors to the maintenance of plasma glucose.
    [Abstract] [Full Text] [Related] [New Search]