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  • Title: Rat intestinal epithelial cell line IEC-6 is activated by recombinant interferon-gamma to inhibit replication of the coccidian Toxoplasma gondii.
    Author: Dimier IH, Bout DT.
    Journal: Eur J Immunol; 1993 Apr; 23(4):981-3. PubMed ID: 8458385.
    Abstract:
    Toxoplasma gondii tachyzoites invaded and replicated in cultured rat small intestine cells of the line IEC-6. Treatment of rat small intestine cells with murine recombinant interferon-gamma resulted in a dose-dependent inhibition of intracellular T. gondii replication. This could be of relevance as a first line defense against Toxoplasma infection.
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