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  • Title: [Oro-esophageal candidiasis resistant to fluconazole in patients with AIDS].
    Author: Diz P, Ocampo A, Miralles C, Otero I, Iglesias I, Martínez C.
    Journal: Enferm Infecc Microbiol Clin; 1993 Jan; 11(1):36-9. PubMed ID: 8461371.
    Abstract:
    BACKGROUND: Fluconazole-resistant Candida albicans has been seldom reported in the literature. in this study, two clinical cases of oro-esophageal candidosis resistant to this antifungal drug are described. METHOD: Infection was confirmed by isolation of yeasts (culture of mouth swabs, oesophagoscopy and histology of biopsy specimens). In vitro antifungal susceptibility tests were performed with standard methods (NCCLS). RESULTS: Clinical and microbiological fluconazole-resistant Candida albicans was isolated. CONCLUSIONS: Causes of development of resistances are commented, and the role of immunodeficiency and the possibility of a Candida strain selection is discussed.
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