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  • Title: Evaluation of extravascular thermal volume in the lung in dogs with endotoxin-induced shock by double indicator dilution method using heat and sodium ions.
    Author: Tagawa M, Okano S, Hara Y, Ejima H, Motoyoshi S, Urakawa N, Furukawa K, Onda M, Ogawa R.
    Journal: J Vet Med Sci; 1993 Feb; 55(1):87-91. PubMed ID: 8461432.
    Abstract:
    Accuracy assessment was undertaken under varying hemodynamic conditions for a lung water volume measurement device which is based on the principle of a double indicator dilution method using heat and sodium ions. Changes in extravascular thermal volume were investigated in dogs with endotoxin-induced shock. The isoproterenol- or propranolol-induced changes in hemodynamics had no effect on the measurement. This confirmed the high accuracy of this measuring method. The measurement revealed a tendency for the extravascular thermal volume to gradually increase (p < 0.05) during endotoxin shock. This confirmed the gradual progression of pulmonary edema during endotoxin shock.
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