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  • Title: [Reversal of small bowel segments to delay intestinal passage after total colectomy (author's transl)].
    Author: Müller G, Kieninger G, Breucha G, Voigt H, Schmidt K.
    Journal: Langenbecks Arch Chir; 1977 Feb 12; 343(3):243-50. PubMed ID: 846282.
    Abstract:
    Five female mini-pigs underwent total colectomy including resection of the ileocecal valve. Sparing the terminal rectum, we reformed an end-to-end anastomosis between terminal ileum and remaining rectal cuff. In a second series 8 female mini-pigs have been colectomized using the same model. To delay intestinal passage, in addition a 10-12 cm long reversed segment of terminal ileum has been inserted between small bowel and rectal stump. Both groups were compared with a group of normal unoperated mini-pigs in a study up to 1 year, observing intestinal transit time, blood chemistry and general development of the animals. It could be proved that the reversal of a small bowel segment in colectomized animals leads to a prolongation of the intestinal transit time, to normalization of electrolytes and general appearance. Colectomy was only survived by animals with a reversed segment. The clinical application of a reversed small bowel segment following total colectomy in 1 patient was successful.
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