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  • Title: Ferrocins, new iron-containing peptide antibiotics produced by bacteria. Isolation, characterization and structure elucidation.
    Author: Tsubotani S, Katayama N, Funabashi Y, Ono H, Harada S.
    Journal: J Antibiot (Tokyo); 1993 Feb; 46(2):287-93. PubMed ID: 8468244.
    Abstract:
    Novel iron-containing peptide antibiotics, ferrocins A, B, C and D, have been isolated from the culture filtrate of Pseudomonas fluorescens YK-310. These antibiotics were purified by butanol extraction, followed by column chromatography using adsorption resin, silica gel and preparative reverse-phase HPLC. The structures of ferrocins were elucidated using spectroscopic and degradative methods. Ferrocins contain three hydroxamate moieties per ferric ion which forms an octahedral iron complex.
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