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  • Title: The role of moclobemide in endogenous depression: a survey of recent data.
    Author: Woggon B.
    Journal: Int Clin Psychopharmacol; 1993 Jan; 7(3-4):137-9. PubMed ID: 8468434.
    Abstract:
    Earlier studies demonstrated that moclobemide has good efficacy as an antidepressant. Its efficacy was comparable to reference antidepressants, both in endogenous and non-endogenous depression. A meta-analysis was performed of recent data from more than 2000 patients who had participated in double-blind trials with moclobemide and comparison drugs. Based on HAMD-17 baseline scores, the sample was divided into three groups according to the severity of depression. In all three, moclobemide was as effective as comparison drugs, both in endogenous and non-endogenous depression. The antidepressant efficacy of both moclobemide and reference drugs was more pronounced in endogenous than in non-endogenous depression, whatever the severity.
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