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  • Title: [A case of Down's syndrome with progressive dementia of Alzheimer type].
    Author: Ishino Y, Mori T, Nakata H.
    Journal: Kaku Igaku; 1993 Feb; 30(2):197-201. PubMed ID: 8468804.
    Abstract:
    A rare case of Down's syndrome complicated with progressive dementia of Alzheimer type in a 41-year-old man was reported. On 123I-IMP SPECT, the patient revealed symmetrical bilateral temporo-parietal hypoperfusion. This finding seemed to support the developing dementia of Alzheimer type on the basis of clinical manifestations. 123I-IMP SPECT seemed to be useful for early diagnosis of Alzheimer-like change in a natural course of Down's syndrome.
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